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On January 10, 2002, CMS also issued a similar letter to AOTAon the subject. The ACGIH has alsogiven the skin notation to nitrobenzene. Some historians of the concept (Boyle 1991) have even demonstrated thatthe symptom profiles recorded in the late nineteenth century – when Kraepelin and Bleuler con-structed the disease entity, first called ‘dementia praecox’ and then ‘schizophrenia’ – bear littlerelationship to the first-rank symptoms that psychiatrists currently use in their diagnoses

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